Monoamine oxidase (MAO) is an enzyme that naturally occurs in our bodies. This enzyme breaks down neurotransmitters such as serotonin, norepinephrine and dopamine, but also psychoactive substances such as psilocin and DMT. Peganum harmala contains harmaline. Harmaline works as MAO inhibitor (MAOi). This means that the MAO enzyme will not be active for several hours. This keeps the above-mentioned substances remain and stack in your system.
There are risks associated with its use. The substance tyramine is not broken down after using a MAOi. When tyramine accumulates in your blood this can increase your blood pressure enormously (hypertension) up to dangerous levels. To prevent this from happening you must therefore ensure that you have as little as possible of tyramine in your food and drinks. It is strongly recommended to do a “MAO diet” at least 12 hours prior to the intake of Peganum harmala